Tshuaj tiv thaiv kab mob Pfizer

2024 Tus sau: James Gerald | [email protected]. Kawg hloov kho: 2023-12-17 14:08

Kev txhaj tshuaj tiv thaiv tus kabmob coronavirus tau ua tiav hauv Suav Tebchaws, Tebchaws Meskas, Tebchaws Askiv, Russia thiab Canada txij thaum pib lub Kaum Ob Hlis. Txog rau tam sim no, ntau dua ib lab tus tib neeg tau txhaj tshuaj tiv thaiv kab mob, thiab cov txheej txheem no tseem tab tom ua. Tam sim no, cov khoom lag luam ntawm kev txhawj xeeb Pfizer thiab lawv tus khub German - BioNTech tau siv. Qhov kev zam yog Russia thiab Tuam Tshoj, uas siv lawv tus kheej cov tshuaj tiv thaiv. Cov tshuaj tiv thaiv kab mob Pfizer coronavirus muaj pes tsawg thiab nws puas nyab xeeb?

Cov tshuaj tiv thaiv BNT162b2 mRNA tiv thaiv COVID-19

Ib qho ntawm cov lus nug feem ntau yog qhov tshwm sim tshwm sim uas yuav tshwm sim tom qab txhaj tshuaj tiv thaiv kab mob. Cov muaj pes tsawg leeg tseem muaj qhov pom tseeb thiab kaw kev sib txuas nrog qhov no. Ntxiv mus, nws tsis pom zoo kom coj nws yog tias koj ua xua rau ib yam ntawm nws cov khoom xyaw.

Dab tsi hauv Pfizer COVID-19 tshuaj tiv thaiv? Nws yog qhov tsim nyog piav qhia thaum pib tias qhov tshuaj tiv thaiv no tsis yog tshuaj tiv thaiv tus qauv thiab tau tsim nrog thev naus laus zis tshiab tshaj plaws. Nws qhov tshwj xeeb nyob hauv qhov tseeb tias nws tsuas muaj ib feem ntawm RNA ntawm tus kab mob, thiab tsis yog tag nrho cov khoom. Yog li, tsis muaj kev pheej hmoo kis mob tom qab txhaj tshuaj tiv thaiv kab mob.

Tus xa xov xwm me RNA no muaj cov ntaub ntawv hais txog cov protein tshwj xeeb uas muaj lub luag haujlwm rau kev sib kis ntawm tus kab mob SARS-CoV-2. Yog li, lub cev tiv thaiv kab mob ntawm tus neeg txhaj tshuaj tau txais cov ntaub ntawv raug tseeb txog yam nws xav tau kom tshem tawm nruab nrab thiab yuav tsum tsim cov tshuaj tiv thaiv dab tsi. Raws li qhov tshwm sim, lub cev tiv thaiv kab mob nco qab cov lus nws tau txais thiab qhib kev tiv thaiv kev tiv thaiv thaum tsim nyog los tawm tsam kev hem thawj.

Cov tshuaj tiv thaiv tiv thaiv tus kabmob coronavirus tseem tau piav qhia raws li hauv qab no: "Cov tshuaj tiv thaiv tiv thaiv COVID-19 BNT162b2 yog qhov ua kom huv ib leeg tus tub txib RNA tau txais los ntawm kev hloov pauv ntxiv hauv vitro los ntawm qhov tsim nyog DNA matrices encoding cov kab mob kis SARS-CoV-2."

Ntxiv rau tus kabmob coronavirus mRNA, cov tshuaj tivthaiv tseem suav nrog:

• ALC-0315 = ((4-hydroxybutyl) azandiyl) bis (hexane-6, 1-diyl) bis (2-hexyl decanoate);
• ALC -0159 = 2 [(polyethylene glycol) -2000] -N, N -ditetradecylacetamide;
• polyethylene glycol / macrogol;
• 1, 2-distearoyl-sn-glycero-3-phosphocholine thiab cov cholesterol;
• poov tshuaj chloride;
• poov tshuaj dihydrogen phosphate;
• sodium tshuaj dawb;
• sodium hydrogen phosphate dihydrate;
• sucrose;
• dej rau kev txhaj tshuaj.

Pob

Cov khoom xyaw no tau nyob ib puag ncig los ntawm cov tshuaj ntsiav me me ua los ntawm lipid nanoparticles. Nws ua ob qho kev tiv thaiv thiab thauj cov haujlwm hauv kev cuam tshuam nrog cov tshuaj hauv, vim nws txhawb nqa lawv nkag mus los ntawm cov cell membrane.

Puas yog txhaj tshuaj Pfizer zoo?

Kev tswj hwm ntawm BioNTech, nws cov tshuaj tiv thaiv tau tsim los koom tes nrog Pfizer, tsis muaj kev poob siab tias cov tshuaj yuav muaj txiaj ntsig zoo. Nws lees paub tias cov tshuaj tiv thaiv yuav muaj txiaj ntsig zoo rau ob qho qub thiab tshiab ntawm tus kabmob coronavirus uas tau tshwm sim hauv tebchaws Askiv. European Medicines Agency (EMA) thiab European Commission tau pom zoo siv tshuaj tiv thaiv los ntawm Pfizer thiab BioNTech hauv cov tebchaws ntawm European Union. Lawv tau lees paub tias cov tshuaj pom 95% ua tau zoo hauv kev sim tshuaj.

Cov tshuaj tiv thaiv Pfizer xav tau 2 koob tshuaj txhua txhua 3 lub lis piam. Thaum Lub Kaum Ib Hlis, Pfizer tau hais tias thawj qhov txiaj ntsig los ntawm theem 3 kev tshuaj ntsuam pom pom tias 2 koob tshuaj tau 95% muaj txiaj ntsig los tiv thaiv Covid-19.

Qhov ua tau zoo tag nrho ntawm cov tshuaj tiv thaiv, raws li cov kws tshawb fawb, zoo ib yam rau txhua pawg hnub nyoog, haiv neeg thiab haiv neeg tsawg, thiab cov neeg muaj comorbidities xws li rog, ntshav qab zib thiab ntshav siab.

Kev phom sij ntawm kev txhaj tshuaj

Cov tshuaj tiv thaiv nug txog puas txaus ntshai? Thaum txhaj tshuaj tiv thaiv kab mob rau hauv lub cev, lub cev tiv thaiv tam sim ntawd ua rau nws - cov tshuaj tiv thaiv kab mob thiab cov cell tiv thaiv kab mob tau tsim. Qee qhov xwm txheej, cov tshuaj tiv thaiv kab mob hauv lub cev tuaj yeem cuam tshuam nrog cov kev mob tshwm sim. Ib yam yuav yog rooj plaub rau BNT162b2 COVID-19 txhaj tshuaj tiv thaiv tsim los ntawm Pfizer.

Raws li cov chaw tsim khoom, feem ntau ntawm cov kev mob tshwm sim me me lossis nruab nrab thiab ploj hauv ob peb hnub txij li lub sijhawm lawv tshwm sim. Yog tias muaj kev phiv xws li mob lossis ua npaws thab tus neeg, siv cov tshuaj paracetamol-based los yog tshuaj tua kab mob tuaj yeem siv tau.

Feem ntau cov kev mob tshwm sim, uas tuaj yeem cuam tshuam ntau dua 1 ntawm 10 tus neeg, yog:

• mob ntawm qhov chaw txhaj tshuaj;
• qaug zog;
• mob taub hau;
• mob nqaij;
• mob caj dab;
• ua daus no;
• kub.

Feem ntau (tsawg dua 1 ntawm 10 tus neeg), cov kev mob tshwm sim no tseem tuaj yeem tshwm sim:

• o thiab liab ntawm qhov chaw txhaj tshuaj;
• lwm yam kev tsis haum tshuaj.

Tsis tshua muaj tshwm sim (tsawg dua 1 ntawm 100 tus neeg), koj yuav ntsib cov qog nqaij hlav o lossis tsis xis nyob.

Cov chaw tsim khoom pom zoo hais tias koj tuaj yeem tshaj tawm cov kev mob tshwm sim rau koj tus kws kho mob lossis kws saib xyuas neeg mob. Qhov no tseem siv rau ib qho kev xav tsis zoo uas tsis muaj npe raws li ua tau.

Qhov tshwm sim ntawm kev txhaj tshuaj tiv thaiv tom qab txhaj tshuaj yog ib qho teeb meem ntawm tus kheej. Qee cov tsos mob tuaj yeem lossis yuav tsis tshwm sim txhua txoj kev.

Tsis zoo tom qab txhaj tshuaj tiv thaiv kab mob

Kev txhaj tshuaj tiv thaiv kab mob yog qhov xav tau los ntawm lub cev cuam tshuam nrog kev tiv thaiv kab mob thiab tsim cov tshuaj tiv thaiv kab mob. Qhov tshwm sim ntawm cov tshuaj tiv thaiv tom qab txhaj tshuaj yog nyob ntawm hom kev txhaj tshuaj, nws muaj pes tsawg leeg thiab tus yam ntxwv ntawm tus neeg uas nws tau muab rau. Feem ntau, lub hauv paus ntsiab lus ntawm kev txhaj tshuaj tiv thaiv yog xws li cov kev mob tshwm sim tau txwv rau qhov tshwm sim me me, xws li liab liab lossis mob ntawm qhov chaw txhaj tshuaj.

Qhov feem ntau tshwm sim tom qab txhaj tshuaj tiv thaiv kab mob yog tshuaj tiv thaiv kab mob ntsws - tom qab ob peb lub lis piam, kev nkag mus thiab erythema tshwm ntawm qhov chaw txhaj tshuaj. Hauv 95 feem pua ntawm cov tshuaj tiv thaiv, qhov caws pliav tseem nyob tom qab kho tas.

Ntawm qhov tod tes, cov kev tsis zoo tuaj yeem ua rau muaj kev cuam tshuam loj rau kev txhaj tshuaj tiv thaiv ntev tshaj li ob peb hnub, tab sis tsis muaj kev phom sij rau lub neej thiab tsis ua rau muaj kev puas tsuaj rau kev noj qab haus huv.

Raws li WHO, cov tshuaj tiv thaiv hnyav tom qab txhaj tshuaj tiv thaiv yog cov tshuaj tiv thaiv cuam tshuam uas yuav tsum tau mus pw hauv tsev kho mob lossis nce kev nyob hauv tsev kho mob tam sim no. Lawv ua rau txo qis hauv kev ua haujlwm ntawm lub cev thiab lub hlwb, lossis ua rau muaj kev hem thawj rau lub neej.

Cov txiaj ntsig

1. Kev tshuaj xyuas cov ntaub ntawv los ntawm kev sim tshuaj tiv thaiv Pfizer qhia tau tias cov tshuaj tiv thaiv tau zoo 95%.
2. Tebchaws Askiv tau dhau los ua thawj lub tebchaws pom zoo txhaj tshuaj Pfizer. Russia thiab Tuam Tshoj siv kom deb li deb tau tsim los ntawm nws tus kheej inoculating cov ntaub ntawv.
3. Ib yam li cov tshuaj tiv thaiv twg, cov tshuaj tiv thaiv tau tshaj tawm tias muaj peev xwm ua rau muaj kev phiv. Muaj tseeb, cov kws tshawb fawb taw qhia tias feem ntau lawv yog lub teeb thiab tsis cuam tshuam rau kev noj qab haus huv ntawm cov tshuaj tiv thaiv.